“Game of Thrones” may be over, but winter is still coming.

That means the dreaded cold and flu season is right around the corner.

“A visit with a clinician has become increasingly common for upper respiratory symptoms since the COVID pandemic,” Mark Fendrick, M.D., a general internist at the University of Michigan, who is based in Ann Arbor, Michigan, told Fox News Digital.

“However, it is much more likely that cold symptoms will be self-limited and not require more than your favorite home remedy,” added Fendrick, who has studied the common cold.

While there’s no specific treatment for the common cold, there are some instances when antivirals are prescribed to treat the flu, the doctor noted.

“Doctors can only prescribe recommended treatment for specific causes that are less common than the common cold, such as antivirals for influenza or COVID-19 or antibiotics for bacterial infections such as strep throat,” Fendrick said.

It’s important to understand the signs and symptoms that should alert you to seek medical attention when you have a cold or the flu this winter season, he said.

The common cold can be caused by as many as 200 respiratory viruses, but the most prevalent is the rhinovirus, according to the Centers for Disease Control and Prevention (CDC) website.

The flu is caused by influenza viruses that generally infect the nose, throat and sometimes the lungs, per the CDC.

The cold and flu share many of the same symptoms, which means it can sometimes be difficult to tell the difference between the two conditions.

People are generally sicker with the flu, experts agree.

Flu symptoms are more intense and come on quicker than the common cold, which generally has milder symptoms.

“The cold and flu can sometimes be complicated by pneumonia, bacteremia and rarely even central nervous system involvement,” Dr. James H. Conway, pediatric infectious disease physician and medical director of the immunization program at UW Health Kids in Madison, Wisconsin, told Fox News Digital.

When respiratory viruses infect the nose, the body responds by making mucus to help clear out the viruses, according to the CDC.

People may develop nasal congestion, which is more common with colds.

They may also experience sneezing, coughing or a sore throat.

Over the next several days, the mucus may change color to white, yellow or green.

This color change is a natural progression of a cold, so antibiotics that fight bacteria are not typically prescribed, per the CDC.

Most people with colds don’t develop a fever, so that symptom combined with headache and body aches could indicate influenza.

When to seek medical care

Conway recommends watching for symptoms that indicate a cold or flu may have turned into a more serious infection.

These may include higher fevers, he said, since most viral infections don’t generally cause that symptom.

Other warning signs include shaking chills, fast or labored breathing, and any type of bad headache or confusion, he added.

“Any of these viral illnesses can also lead to ear infections or sinus infections,” Conway said.

In those cases, fever with ear pain or facial pain is often seen.